医学
再生(生物学)
结缔组织
清创术(牙科)
牙科
牙周炎
组织工程
再生医学
刮除术
细胞外基质
生物医学工程
牙周病学
干细胞
病理
生物
细胞生物学
出处
期刊:Bioinformation
[Biomedical Informatics]
日期:2022-12-31
卷期号:18 (12): 1181-1185
标识
DOI:10.6026/973206300181181
摘要
Periodontitis is a serious chronic inflammatory condition that can cause periodontal tissue deterioration and, eventually, tooth loss. Periodontal regenerative therapy using membranes and bone grafting materials, as well as flap debridement and/or flap curettage, have all been used with varying degrees of clinical effectiveness. Current resorbable and non-resorbable membranes serve as a physical barrier, preventing connective and epithelial tissue down growth into the defect and promoting periodontal tissue regeneration. The "perfect" membrane for use in periodontal regenerative therapy has yet to be created, as these conventional membranes have several structural, mechanical, and bio-functional constraints. We hypothesised in this narrative review that the next-generation of guided tissue and guided bone regeneration (GTR/GBR) membranes for periodontal tissue engineering will be a graded-biomaterials that closely mimics the extracellular matrix.
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