滋养层
基因亚型
细胞生物学
功能(生物学)
细胞色素c氧化酶
线粒体
化学
细胞色素c
生物
生物化学
胎盘
胎儿
怀孕
基因
遗传学
作者
Jian Yu,Yaoyun Duan,Qin Lu,Miaojuan Chen,Ning Fang,Yixin Ye,Shenjiao Lu,Deqiong Ou,Xiaoyan Sha,Xiao-Wen Gan,Ming Zhao,Gendie E. Lash
标识
DOI:10.1016/j.placenta.2024.04.011
摘要
Spontaneous miscarriage is a common complication of early pregnancy. Previous studies have shown that mitochondrial function plays an important role in establishment of a successful pregnancy. Cytochrome c oxidase subunit 4 isoform 1 (COX4I1), a component of electron transport chain complex Ⅳ, is required for coupling the rate of ATP production to energetic requirements. However, there is very limited research on its role in trophoblast biology and how its dysfunction may contribute to spontaneous miscarriage.
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