电流(流体)
热疗
癌症
磁性纳米粒子
纳米颗粒
国家(计算机科学)
医学
纳米技术
计算机科学
材料科学
内科学
工程类
电气工程
算法
作者
Marzena Szwed,Agnieszka Marczak
出处
期刊:Cancers
[MDPI AG]
日期:2024-03-14
卷期号:16 (6): 1156-1156
标识
DOI:10.3390/cancers16061156
摘要
Hyperthermia (HT) is an anti-cancer therapy commonly used with radio and chemotherapies based on applying heat (39–45 °C) to inhibit tumor growth. However, controlling heat towards tumors and not normal tissues is challenging. Therefore, nanoparticles (NPs) are used in HT to apply heat only to tumor tissues to induce DNA damage and the expression of heat shock proteins, which eventually result in apoptosis. The aim of this review article is to summarize recent advancements in HT with the use of magnetic NPs to locally increase temperature and promote cell death. In addition, the recent development of nanocarriers as NP-based drug delivery systems is discussed. Finally, the efficacy of HT combined with chemotherapy, radiotherapy, gene therapy, photothermal therapy, and immunotherapy is explored.
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