生物
蛋白质组
微生物种群生物学
代谢组
枯草芽孢杆菌
粗脉脉孢菌
巢状曲霉
细菌
代谢组学
发酵
基因组
微生物
微生物学
生物技术
食品科学
生物化学
遗传学
生物信息学
基因
突变体
作者
Liang Yang,Wenlai Fan,Yan Xu
标识
DOI:10.1016/j.fm.2022.104144
摘要
Chameleon-like microbes in the fermentation community are an internal factor that facilitate the transformation of the community to the corresponding homeostasis states under specific environmental conditions. High temperature daqu can form three typical microecologies during the preparation process, making it an ideal system for studying chameleon-like microbes. This study integrated multi-omic methods such as metaproteomics, and determined that Neurospora crassa, Aspergillus nidulans, Bacillus subtilis and Oceanobacillus iheyensis were chameleon-like microbes that regulated the metabolic differences of five-member heterocyclic amino acids in daqu, resulting in microecological differentiation. Synthetic microbial consortia consisting of the four chameleon-like microbes with (T6) and without (T4) the dominant functional bacteria Saccharopolyspora erythraea and Virgibacillus haloimitrificans were fermented under simulated in situ conditions. The community constructed by microorganisms with greater functional diversity (T6) was more robust, and its metabolome was more similar to the in situ system. When exposed to environmental disturbances, the functional diversity helped to maintain the community stability by increasing the dissimilarity of chameleon-like microbes in the community and forming different homeostasis.
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