Pseudopterane and Norcembrane Diterpenoids from the Caribbean Sea Plume Pseudopterogorgia acerosa

A chemical study of the common Caribbean sea plume Pseudopterogorgia acerosa from Puerto Rico has produced two previously undescribed secondary metabolites. One of them, 1, is a new representative of the pseudopterane family of diterpenes possessing the uncommon 3,4;5,6 diepoxyfuran moiety. The other metabolite, 2, is a rare norcembranolide diterpene. Their chemical structures, including relative stereochemistry, were established by detailed analysis of the spectral data in addition to NMR spectral comparisons with known pseudopterane and cembrane models.