Controlled in situ synthesis of surface functionalized BaSO4 nanoparticles for improved bone cement reinforcement

Controlled in situ synthesis of surface functionalized BaSO4 nanoparticles is achieved by using a difunctional molecule to modulate the growth of nanoparticles coupled with in situ generation of SO42− under mild conditions. Such BaSO4 nanoparticles with surface vinyl groups reinforce the PMMA bone cement better than conventional BaSO4 particles.