医学
血栓形成
无症状的
深静脉
抗凝剂
低分子肝素
重症监护医学
并发症
导管
入射(几何)
外科
流行病学
癌症
静脉血栓形成
内科学
物理
光学
作者
Arnaldo Marín,Leonardo Bull,Matthew Kinzie,Max Andresen
出处
期刊:BMJ supportive & palliative care
[BMJ]
日期:2021-08-19
卷期号:11 (4): 371-380
被引量:14
标识
DOI:10.1136/bmjspcare-2019-002106
摘要
The adequate handling of central venous catheters is a key element in the management of patients with cancer. Catheter-associated deep vein thrombosis is frequently observed in patients with malignant diseases; however, despite being a common complication among these patients, objective information concerning its epidemiology, clinical course, prophylaxis and treatment strategies is very limited. The reported incidence of catheter-related thrombosis (CRT) is highly variable, depending on symptomatic events, or if patients are screened for asymptomatic thrombosis. Several factors have been identified as potential predisposing factors for CRT, both technical and pathological aspects. The anticoagulant of choice is still unclear; while low-molecular-weight heparin is most commonly used, recent studies assessing the role of direct oral anticoagulants in the treatment of CRT show promise as an alternative, but the evidence remains insufficient and the decision must be made on a case-by-case basis.
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