氧化应激
材料科学
免疫疗法
免疫原性细胞死亡
癌症研究
细胞内
肿瘤微环境
阿霉素
谷胱甘肽
医学
化疗
免疫系统
药理学
免疫学
细胞生物学
生物
生物化学
内科学
酶
肿瘤细胞
作者
Linping Zhao,Rongrong Zheng,Lingshan Liu,Xiayun Chen,Runtian Guan,Yang Ni,Ali Chen,Xiyong Yu,Hong Cheng,Shiying Li
出处
期刊:Biomaterials
[Elsevier BV]
日期:2021-06-14
卷期号:275: 120970-120970
被引量:78
标识
DOI:10.1016/j.biomaterials.2021.120970
摘要
Amplifying oxidative stress to break intracellular redox homeostasis could accelerate tumor cell death. In this work, a self-delivery oxidative stress amplifier is developed for chemotherapy sensitized immunotherapy. By virtue of the π-π stacking and coordination effect, copper ions (Cu
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