[The detection of cortisol level in blood plasma of patients with arterial hypertension at resistance to stress impacts of various degree.]

The analysis was applied to the results of detection of level of cortisol in pre-operational period before planned arthroscopy in 63 patients (aged from 45 to 50 years) with hypertension disease stage I and II with different stress resistance. The stress resistance was detected using such tests as Perceived Stress Scale (PSS) and the Depression, Anxiety and Stress Scale (DASS). In most of patients, the analysis of results of testing demonstrated an average level of stress and and average anxiety before the operation. 20 stress resistant patients and 43 stress non-resistant patients were picked out. The level of cortisol in pre-operational period turned out reliably higher in patients with low stress resistance. The data analysis according results of day monitoring of blood pressure prior to implementation of arthroscopy established that in stress non-resistant patients a more expressed increasing of velocity of morning rising of systolic and diastolic blood pressure as compared to stress resistant patients. After surgical intervention, velocities of morning rising of systolic and diastolic blood pressure also were higher in stress non-resistant patients. They also had lower values of day index of systolic blood pressure (non-dipper). In stress resistant patients, day index of systolic blood pressure before and after was within the limits of standard values. The average values of systolic and diastolic blood pressure registered within limits of on standard values. However, they were higher in pre- and post-operational periods among patients with low stress resistance. The received results reflect alteration of function of cardio-vascular system in response to psychological stress that is more expressed in patients with low stress resistance.