医学
类风湿性关节炎
类风湿因子
硬皮病(真菌)
口干
系统性硬皮病
舍格伦综合征
皮肤病科
并发症
抗体
免疫学
胃肠病学
内科学
自身免疫性疾病
皮肌炎
唾液
接种
出处
期刊:Lupus
[SAGE]
日期:2018-10-01
卷期号:27 (1_suppl): 32-35
被引量:78
标识
DOI:10.1177/0961203318801673
摘要
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder characterized by focal lymphocytic infiltration of the exocrine glands causing dry eyes and dry mouth. Similar glandular features can also occur as a late complication in patients with other rheumatic disorders, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and scleroderma (‘secondary’ Sjögren's syndrome). 1 Anti-Ro and/or anti-La (ENA) antibodies are found in approximately 70% of pSS patients, generally with ANA positivity. Hypergammaglobulinaemia is also common. Systemic features also occur in some patients with pSS. A positive rheumatoid factor (RF) is often seen and so if patients present with arthritis, dryness and a positive RF a diagnosis of pSS should be considered as a possible alternative to RA. Anti-CCP antibodies are more specific for RA.
科研通智能强力驱动
Strongly Powered by AbleSci AI