医学
营养不良
不利影响
血液透析
体质指数
内科学
观察研究
疾病
肾脏疾病
重症监护医学
作者
Kazuhiro Toyoda,Takahiro Kuragano,Hiroaki Kawada,Tomo Taniguchi,Takeshi Nakanishi
出处
期刊:Blood Purification
[S. Karger AG]
日期:2019-01-01
卷期号:47 (Suppl. 2): 3-11
被引量:8
摘要
Background/Aim: In maintenance hemodialysis (MHD), protein-energy malnutrition and chronic inflammation can be critical and are two of the main causes of mortality. Method: We compared the change in nutrition and inflammatory conditions between younger and older MHD patients during a 2-year period. Furthermore, using Kaplan-Meier analysis, we evaluated the correlations between changes in each parameter and any adverse events. Result: During the observational period, body mass index (BMI) and serum albumin levels decreased significantly in older patients. In Kaplan-Meier analysis, patients who showed a decline in BMI had an associated elevated risk for cerebro-cardiovascular disease and hospitalization. Moreover, patients who showed a decline in albumin also had an associated higher risk for infectious disease and hospitalization. Conclusion: This study revealed that the downward trend in nutritional status was prominent in elderly patients. Furthermore, changes in nutritional and inflammatory conditions during MHD were associated with adverse events in MHD patients.
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