Iron‐Catalyzed Ring‐Opening/Allylation of Cyclobutanone Oxime Esters with Allylic Sulfones

Abstract An iron‐catalyzed radical allylation of cyclobutanone oxime esters with allylic sulfones via C−C bond cleavage is reported. This protocol provides a straight‐forward approach to cyanoalkylated alkenes with good functional group tolerance and high regioselectivity. Furthermore, this reaction can be further expanded to ring‐opening of less‐strained cyclopentanone oxime esters, leading to desired cyanoalkylated alkenes in good yields. magnified image