Cachexia is the result of interaction between host and tumor,with main manifestations like weight loss in short-term,malnutrition and so on.The inflammatory cytokines secreted by host cells and cachexia specific factor secreted by tumor are the main causes of cachexia.High-energy diet alone can not improve the condition.Recently,immunonutrition,traditional medicine and drug intervention can alleviate the weight loss and prolong survival in cachexia.