Neurogenesis in the Adult Subventricular Zone

The neurogenesis in subventricular zone(SVZ), which is located in the lateral wall of the lateral ventricle, is observed throughout the lifetime in mammalian. The studies suggested neurogenesis could be stimulated further by pathological processes and newly generated neurons might be capable of replacing loss cells in neurological diseases. This paper overviewed the source, composition and architecture of the adult SVZ neurogenesis and the progress of the correlationship between SVZ neurogenesis and neurodegenerative diseases in the recent years.