生物
诱导多能干细胞
精神分裂症(面向对象编程)
干细胞
细胞培养
癌症研究
细胞生物学
遗传学
胚胎干细胞
基因
精神科
心理学
作者
Meixiang Jiang,Yuxing Long,Yiliang Liu,Ran Li,Jingyi Xu,Tongyue Chi,Menglu Sun,Miao Li,Hao Yu,Lu Yu,Xiaobo Han
标识
DOI:10.1016/j.scr.2024.103570
摘要
We obtained Peripheral blood mononuclear cells (PBMCs) from a peripheral blood sample of a 19-year-old male schizophrenia patient and successfully established induced pluripotent stem cell (iPSC) line using non-integrated reprogramming technology. This cell line possesses the correct karyotype, shape of an embryonic stem cell, the ability to express particular pluripotency markers, and the capacity to differentiate into three germ layers in vitro. This cell line will serve as an in vitro model for upcoming studies on the etiology of schizophrenia and the creation of novel treatment.
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