In situ formation of J-aggregate in the tumor microenvironment using acidity responsive polypeptide nanoparticle encapsulating galactose-conjugated BODIPY dye for NIR-II phototheranostics

Galactose-conjugated BODIPY dye and polymeric nanoparticles with H-aggregates were obtained. In the tumor microenvironment pH, J-aggregates are formed in situ , which showed efficient switch-on NIR-II imaging-guided photothermal therapy.