易普利姆玛
前列腺癌
医学
免疫系统
肿瘤科
内科学
前列腺
癌症
免疫学
免疫疗法
作者
Sumit K. Subudhi,Luis M. Vence,Hao Zhao,Jorge Blando,Shalini S. Yadav,Qing Xiong,Alexandre Reuben,Ana M. Aparicio,Paul G. Corn,Brian F. Chapin,Louis L. Pisters,Patricia Troncoso,Rebecca S. Tidwell,Peter F. Thall,Chang‐Jiun Wu,Jianhua Zhang,Christopher L. Logothetis,P. Andrew Futreal,James P. Allison,Padmanee Sharma
标识
DOI:10.1126/scitranslmed.aaz3577
摘要
Low–tumor mutational burden prostate tumors express neoantigens that elicit T cell responses associated with favorable clinical outcomes to ipilimumab.
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