哒嗪
芳基
化学
溶剂
组合化学
药物化学
有机化学
烷基
作者
Mogili Sumakanth,V. Malla Reddy,V.S.H. Krishnan,B.S. Sastry
出处
期刊:International journal of pharmaceutical sciences and nanotechnology
[BSP Books Private Limited]
日期:2009-05-31
卷期号:2 (1): 471-476
标识
DOI:10.37285/ijpsn.2009.2.1.14
摘要
Several 2,6-diaryl-imidazo[1,2-b]pyridazines (5 & 7) were prepared from 3-amino-6-aryl-pyridazines (3) which in turn were obtained from the corresponding 6-aryl-pyridazine-3(2H)-ones(1) via., 6-aryl-pyridazin-3(2H)-thiones (2) as intermediates, by a reaction with an appropriate a-halocarbonyl compounds (4) or a-haloacyl carbamates (6) in a suitable solvent at reflux temperature. The resulted products were characterized by their physical, analytical and spectral data.
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