Determination of rosmarinic acid in different populations and parts of Perilla frutescens by HPLC

Rosmarinic acid of 14 different populations and parts of Perilla frutescens was determinated by HPLC method,and all data will be analysed and discussed,then cluster analysis were performed too. The results showed that the content of rosmarinic acid in leaves,ears,stems and roots between 14 kinds of P. frutescens were significantly differenct(P0.05),the rosmarinic acid content in different parts among the same population also had significant differences(P0. 05).The contents of rosmarinic acid in leaves from various sources were the highest. The content of rosmarinic acid in ears were higher than in stems in most of the collected popiulations. 14 copies of P. frutescens materials could be divided into4 groups by the cluster analysis. The manuscript displayed that the eras of P. frutescens would be a potential new drug source. The content of rosmarinic acid in P. frutescens materials from the middle and lower reaches of the yangtze river were higher than those from southwest regions.