Objective To compare the advantages and the disadvantages among the different anesthesia methods in children for tonsillectomy and adenoidectomy.Methods 90 cases with ASA I scheduled for tonsillectomy and adenoidectomy.The children were randomly divided into three groups.Patients in group I received Fentanil combined with Isoflurane general anesthesia;patients in group II received Remifentanil combined with Propofol general anesthesia and patients in group III received Remifentanil combined with Propofol and Tramadol general anesthesia.Observing SBP、DBP、HR、SPO2 at the time that before inducing,inserting tube,adenoidectomy,pulling out tube, the recovery time,incidental of side effect,and post operative pain score VAS.Results Tthere were no significant difference on the SBP、DBP、HR、SPO2 at the time before induction,intubation.After adenoidectomy in these three groups(P 0.05). SBP、DBP、HR in group I were larger than in group II,III(P 0.05)at the time after extubation. The recovery time of anesthesia was significantly longer in the group I than in the group II,III incidena of the upper respiratory tract obstruction,nausea,vomiting,and restless more were higher in the group I than in the group II,III(P0.05).Post operative pain score was significantly higher in the group II than in the group I and III(P 0.05).Conclusions remifentanil combined with Propofol and Pramadol general anesthesia is a effective anesthesia methods for tonsillectomy and adenoidectomy in children,and it can wake induce stably,recover fast,and completely.