A Mild Glycosylation Protocol with Glycosyl 1‐Methylimidazole‐2‐carboxylates as Donors

Abstract A mild glycosylation protocol is developed by using glycosyl 1‐methylimidazole‐2‐carboxylates. Such a glycosylation can be promoted by a series of metal triflates and triflimides, especially Cu(OTf) 2 . The reaction is initiated by activation of the glycosyl ester donor via coordination with the metal cation assisted by the adjacent 1‐methylimidazole chelating group.