Research Progress on Synthesis of Nitric Oxide Donor Compounds

Nitric oxide as a biological messenger or effector molecule plays an important physiological role in the body.Owing to its various biological activities, it has received wide attention in clinical practice.Insufficient NO production in vivo is closely related with a variety of diseases.NO donor compounds can release NO in vivo to treat and prevent many diseases.With its wide application in medicine, the methods for the synthesis of NO donor compounds have attracted much attention of researchers.In this paper, the recent advances in the past 10 years in synthetic methods for NO donor compounds are reviewed.