自噬
化学
安普克
ULK1
灵芝
灵芝
细胞生物学
生物化学
激酶
蛋白激酶A
细胞凋亡
食品科学
生物
作者
Rongcan Luo,Yi Luo,Da-Shuang Fang,Yong‐Gang Yao,Ming‐Hua Qiu,Xing-Rong Peng
摘要
Ten structurally diverse A-seco-nortriterpenoids were isolated from the fruiting bodies of Ganoderma cochlear . Compounds 1–4 significantly inhibited tau pathology by inducing autophagy mediated by AMPK-ULK1 pathway.
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