Photoredox deoxygenative allylation of carboxylic acids via selective 1,6-addition of acyl radicals to electron-deficient 1,3-dienes

We report the 1,6-addition of acyl radicals to the electron-deficient 1,3-dienes under visible-light photoredox catalysis. The deoxygenative allylation of the carboxylic acid is achieved under mild conditions, generating the valuable 1,6-dicarbonyl compounds in moderate to good yields (up to 96%). A range of functionalized carboxylic acids are competent coupling partners. This deoxygenative allylation protocol has a high level of regio- and stereo-selectivity as well as good functional group comparability.