Beta-Sitosterol: A Comprehensive Review of Occurrence in Plants and its Therapeutic Potential in Treatment of Cardiovascular Disorders

Introduction: Phytosterols play a major role in the management of cardiovascular diseases. Beta-sitosterol sourced from various plants showed better therapeutic activity and mechanism in treating cardiovascular diseases. However, there has been no comprehensive review of the distribution of beta-sitosterol and its therapeutic activities in cardiac diseases. Methods: Thus, the review includes the occurrence and relevance of beta-sitosterol with its therapeutic outcomes on cardiac diseases. The literature collection process was conducted using scientific databases such as Pubmed, science direct, Google Scholar and books for the concise evaluation of the study. Results: The resultant review on beta-sitosterol has been concised to its biological sources and the process of isolation, therapeutic efficacy against the management of cardiovascular diseases by decreasing the cholesterol absorption which leads to a decrease in Low-density Lipoprotein (LDL) levels. Conclusion: Further preclinical and clinical studies can be explored to explore the efficacy of beta-sitosterol.