化学
重氮
卡宾
叶立德
硼
氧离子
过渡金属
药物化学
衍生化
组合化学
有机化学
催化作用
离子
高效液相色谱法
作者
Zhicheng Bao,Jianbo Wang
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2023-06-05
卷期号:34 (18): 2071-2084
被引量:4
摘要
Abstract Insertion reactions of carbenes or ylides with organoboronic acids or their derivatives have emerged as valuable methods for coupling or homologation of organoboron compounds under metal-free conditions. The crucial steps of these reactions are coordination of the electron-rich carbon centers of the carbene precursors or ylides to the electron-poor boron center, followed by 1,2-migration of the corresponding tetracoordinated boron intermediates. This type of unique transformation provides an efficient method for the construction of C–C or C–X (X = H, B) bonds. Moreover, the C–B bonds generated by such transformations can be utilized as a handle for further derivatization or iterative homologations. In this Account, we summarize the developments in this arena according to the reactive diazo compound, N-arylsulfonylhydrazone or ylide species involved. 1 Introduction 2 Reactions with Diazo Compounds 3 Reactions with N-Arylsulfonylhydrazones 4 Reactions with Ylides 5 Conclusion
科研通智能强力驱动
Strongly Powered by AbleSci AI