A Robust Infinite Zirconium Phenolate Building Unit to Enhance the Chemical Stability of Zr MOFs

Abstract A novel Zr‐chain based MOF, namely MIL‐163, was designed and successfully synthesized using a bis‐1,2,3‐trioxobenzene ligand. Endowed with large square‐shaped channels of 12 Å width, it shows remarkable water uptake (ca. 0.6 cm 3 g −1 at saturating vapor pressure) and a remarkable stability in simulated physiological media, where archetypical Zr carboxylate MOFs readily degrade.