Cobalt(II)‐Catalyzed C−H/N−H Functionalization and Annulation of N‐(quinolin‐8‐yl)benzamide with Cyclopropanols

Abstract A new method for Co‐catalyzed C−H/N−H functionalization and [4+1] annulation of N‐( quinolin‐8‐yl)benzamide with cyclopropanols was developed. This protocol tolerates a variety of functional groups, thereby providing an efficient method for the fabrication of isoindolin‐1‐ones. Moreover, the utility of this strategy was showcased by the late‐stage modification of lithocholic acid derivatives and ibuprofen derivatives.