菌血症
流行病学
医学
抗性(生态学)
结果(博弈论)
重症监护医学
微生物学
内科学
生物
数学
抗生素
生态学
数理经济学
作者
Sirous Jafari,Alireza Abdollahi,Marjan Sabahi,Mohammadreza Salehi,Ali Asadollahi‐Amin,Malihe Hasannezhad,Arash Seifi
出处
期刊:Infectious disorders drug targets
[Bentham Science]
日期:2022-03-01
卷期号:22 (2)
被引量:1
标识
DOI:10.2174/1871526520999201103191829
摘要
An increase in resistant gram-positive cocci, especially enterococci, requires an epidemiologic re-assay and its results may affect empirical treatments for these infections.In this study, we investigated the microbial epidemiology and resistance pattern of enterococcal bacteremia.This study was a cross-sectional study that investigated all cases of positive blood cultures with Enterococcus spp. at a tertiary referral colligates hospital in Tehran in 2018.Enterococcus spp. was isolated from blood cultures of a total of 73 patients. Most of the patients were male i.e: 42 (57.7%). The mean age of the patients was 58.8 (±18.8) years. Hospital- acquired infection was the most prevalent type of infection involving enterococcal bacteremia (80.8%) compared with community-acquired (6.7%) and the health care-associated one (12.3%). Renal failure and cancer were the most underlying disease in E. faecalis and E. faecium, respectively. Mortality for Vancomycin-resistant enterococci (VRE) was approximately two times more than the sensitive ones. Between the dead/alive groups, the following items were significantly different (P.Value<0.05): Vancomycin resistance for enterococcus isolated, immunodeficiency as an underlying disease, Mechanical ventilation, hospitalization period, and the empiric regimen.Increased antibiotic-resistant strains, especially Vancomycin-resistant enterococci (VRE), pose a serious threat to the general public, especially hospitalized patients, causing an increase in mortality. Surveillance of microorganisms and antimicrobial resistance is a crucial part of an efficient health care system.
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