Fusarium wilt, caused by Fusarium oxysporum f.sp. cubense (Foc), is the most important disease of bananas in India. There is no effective control measure for this disease other than the use of resistant cultivars. The objective of this study was to evaluate newly available fungicides under in-vitro and in-vivo conditions for their efficacy against the responsible pathogen Fusarium oxysporum f. sp, cubense (Foc). Results are proved that stem injection with carbendazium (0.3%) + copper oxychloride (0.3%) + Boric acid (0.3%) 30 ml twice at 20 days intervals has maximum recovery after 10-15 days after first injection. However, injection with carbendazium (0.3%) + COC (0.3%) and carbendazium (0.3%) + Boric acid (0.3%) delayed recovery upto 35-45 days. Therefore, for the management of panama wilt of Banana can be managed by combined application of carbendazium (0.3%) + copper oxychloride (0.3%) + Boric acid (0.3%) 30 ml.