Clinical Effect of HCPT+DDP+CF and 5-Fu on the Treatment of 54 Cases of PhaseIV Gastrointestinal Cancer

Objective To observe the clinical effect and side reactions of HCPT+DDP+CF and 5-Fu on the treatment of phase Ⅳ gastrointestinal cancer.Methods 54 cases of phase Ⅳ gastrointestinal cancer were treated with the regimen of HCPT+DDP+CF and 5-Fu for more than two cycles.Results Three of 54 cases got the complete response and twenty two part response.The total response rate was 51.8%.The major side reactions were gastrointestional tract reaction,myelosuppression,temporary kidney functional damage and alopecia.Conclusion The regimen of HCPT+DDP+CF and 5-Fu is effective in the treatment of phase Ⅳ gastrointestinal cancer,and well tolerated.