Ethylene production in non-climacteric fruit is far lower than that of climacteric fruit,which led to the previous conclusion that ethylene played very limited role in regulating ripening and senescence of non-climacteric fruit since 1970s.However,due to the economical importance of many non-climacteric fruit such as citrus,strawberry,grape,loquat,etc,more research work have been reported for such fruit recently.Evident results show that many ripening related processes in non-climacteric fruit are also ethylene regulated,and non-climacteric fruit and climacteric fruit share some similar molecular regulation mechanisms during the changes of fruit quality.Research advance in regulation of ethylene during ripening and senescence of non-climacteric fruit are reviewed in this paper.