医学
纤维化
Notch信号通路
非酒精性脂肪肝
肝纤维化
病理
脂肪肝
内科学
受体
疾病
标识
DOI:10.1056/nejmcibr1815636
摘要
Data obtained from humans and a mouse model of liver fibrosis implicate Notch signaling in the induction of liver fibrosis in the presence of lipid accumulation and show (in mice) that suppression of Notch signaling ameliorates fibrosis.
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