生物
纤毛
高尔基体
GTP酶
细胞生物学
系统发育树
遗传学
胚胎干细胞
作者
Skylar I Dewees,Romana Vargová,Katherine R Hardin,Rachel E Turn,Saroja Devi,Joshua Linnert,Uwe Wolfrum,Tamara Caspary,Marek Eliáš,Richard A. Kahn
标识
DOI:10.1091/mbc.e21-10-0509-t
摘要
Phylogenetic analyses of ARF family GTPases predict that ARL16 is linked to cilia. This was confirmed using mouse embryonic fibroblasts deleted for ARL16, resulting in defects in Golgi-to-cilium traffic, with accumulation of IFT140 and INPP5E at Golgi.
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