Water-Soluble Viscosity-Activated Molecular Rotor for In Situ Imaging of Liver Damage in the NIR-II Window

-induced fibrosis, and diet/drug-induced steatosis. Signal changes correlate with standard biochemical and histological markers and decrease after treatment. These findings identify PEGylated NIR-II molecular rotors as promising tools for noninvasive, real-time mechanism-based assessment of liver disease.