强脉冲光
眼睑炎
眼睑
睑板腺
皮肤病科
医学
酒渣鼻
眼科
蠕形螨
螨
生物
植物
痤疮
出处
期刊:Photobiomodulation, photomedicine, and laser surgery
[Mary Ann Liebert]
日期:2023-03-01
卷期号:41 (3): 104-119
被引量:2
标识
DOI:10.1089/photob.2022.0120
摘要
Objective: To evaluate relevant clinical outcomes and conclude possible mechanisms of intense pulsed light (IPL) in eyelid inflammation. Background: IPL devices were primarily applied in cutaneous vascular malformations and have been used in ocular diseases for about 20 years, mostly including meibomian gland dysfunction (MGD), blepharitis, and ocular rosacea. Recent findings: Seventy-two original clinical researches were included, 57 for MGD, 4 for blepharitis or blepharitis-related keratoconjunctivitis, and 11 for rosacea. Dry eye symptoms, (tear) break-up time (BUT), and meibomian structure and/or functions were improved in most patients, but production of reactive oxygen species is an important link in the photobiomodulation mediated by IPL, which can influence numerous signal pathways to achieve anti-inflammatory, anti-infective, and prodifferentiation effects. Conclusions: The evidence suggests that IPL is an effective therapeutic tool for most patients with MGD, but more clinical evidence is needed for other indications.
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