Aquaculture endows the rising tide of antimicrobial resistance among bacterial pathogens along with increasing incidences of bacterial disease outbreaks which calls for the urgent requirement of alternative anti-bacterial agents than antibiotics. One such promising treatment is the use of phage therapy in aquatic farming, which is re-gaining huge scientific attention since the past few decades and great bactericidal potential is reported by extensive in vitro and in vivo studies. Phage therapy holds potential as a relatively inexpensive and low environmental impact biocontrol approach. Therefore, we aim to document the important aspects of phage therapy including the advantages as well as possible drawbacks associated with their use. A logical selection of phages based on the outlined characteristics is necessary to meet requirements of a successful treatment and global acceptance