鞣花酸
化学
没食子酸甲酯
没食子酸
区域选择性
没食子酸丙酯
产量(工程)
立体化学
有机化学
多酚
组合化学
抗氧化剂
没食子酸
催化作用
核化学
材料科学
冶金
作者
Maria Dolors Pujol,Salha Hamri,Olga Abián,Marc Viñas,Daniel Jahani,Jaume Ginard,Francesc Navarro,Rosa Reches,Josep Vilardell
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2022-09-12
卷期号:55 (04): 657-662
被引量:1
摘要
Abstract A practical synthesis of ellagic acid has been achieved from methyl gallate by a proposed synthetic route of five steps, consisting of ketal protection, regioselective bromination, bis-lactonization, C–C bond formation between the aromatic rings of the galloyl groups, and ketal deprotection, in 38% overall yield. Ellagic acid showed a slight inhibitory activity against SARS-CoV-2 3CLpro.
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