血小板活化
内皮细胞活化
血小板
血栓
医学
血栓形成
糖尿病
内科学
P-选择素
止血
内分泌学
炎症
作者
Zhiyu Li,Jiachen Zhang,Zejun Ma,Guobing Zhao,Xue He,Xuefang Yu,Qiang Fu,Naishi Wu,Zhongren Ding,Haipeng Sun,Xu Zhang,Yi Zhu,Liming Chen,Jinlong He
标识
DOI：10.1161/atvbaha.123.319835
摘要
Collectively, our data suggest that hyperglycemia-induced endothelial YAP activation aggravates platelet activation and arterial thrombus formation via PGE2/EP3 signaling. Targeting EP3 with DG-041 might be therapeutic for diabetes-related thrombosis.
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(2025-6-4)
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