In situoxidative polymerization of platinum(iv) prodrugs in pore-confined spaces of CaCO3nanoparticles for cancer chemoimmunotherapy

Pt(iv)SS@CaCO3@Biotin can interact in cisplatin-resistant non-small lung cancer cells by a multimodal mechanism of action, triggering cell death by a combination of by apoptosis, ferroptosis, and immunogenic cell death in vitro and in vivo .