医学
心肌梗塞
促炎细胞因子
心肌保护
磷酸二酯酶
内科学
心脏病学
再灌注损伤
冠状动脉
炎症
缺血
动脉
生物
生物化学
酶
作者
Qing Wan,Chuansheng Xu,Liyuan Zhu,Yuze Zhang,Zekun Peng,Hong Chen,Haojie Rao,Erli Zhang,Hongyue Wang,Fei Chu,Xuan Ning,Xuejian Yang,Jinqing Yuan,Yongjian Wu,Yü Huang,Shengshou Hu,De‐Pei Liu,Miao Wang
出处
期刊：Circulation Research
[Ovid Technologies (Wolters Kluwer)]
日期：2022-07-28
卷期号：131 (5): 442-455
被引量：59
标识
DOI：10.1161/circresaha.122.321365
摘要
PDE4B is critically involved in neutrophil inflammation and microvascular obstruction, leading to MI/R injury. Selective inhibition of PDE4B might protect cardiac function in patients with acute myocardial infarction designated for reperfusion therapy.
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(2025-6-4)
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