Collagen Microparticles in Drug Delivery

Targeting delivery and controlled release devices for macromolecular drugs delivery make a big challenge to microparticle drug delivery system,especially the drug carriers.Collagen is an interesting natural material for the preparation of microparticles.The attractiveness of collagen rests on its high biocompatibility and low immunogenicity.This article highlights collagen microparticles' present status as a carrier in drug delivery,including:collagen-coated microspheres,the preparation of collagen microparticles and collagen composites.