Effect of atorvastatin on acute coronary syndrome

Objective: To observe the clinical therapeutic effect and safety of dose-respanse atorvastatin on acute coronary syndrome.Methods: A total of 84 cases of acute coronary syndrome were randomly divided into two groups.They were treated with atorvastatin.Atorvastatin administered subgroup were treated with atorvastatin(80 mg/d qN po) for 2 weeks,and then they were treated with atorvastatin(20 mg/d qN po).At the same time,patients in observation group were treated with atorvastatin(20 mg/d,qN po).After 3 months we compare level of blood lipid,cardiac events and safety of atorvastatin.Results: After 3 months tota1 cholestero1(TC),low density 1ipoprotein cholestero1(LDL-C) and high-sensitivity C-reactive protein(hs-CRP) were significantly reduced in two groups.But the administered subgroup is more efficacious than observation group.Conclusion: Intensive lipid lowering is safe and effective in pantients of acute coronary syndrome.