The mechanisms of hydroxamic acid as collectors on flotation,hydroxylamine method for synthesis of hydroxamic acid,and synthetic methods are brifely introduced and sorted.The development of hydroxylamine method,including four reaction mediums such as alcohols,alcohols/water,aqueous and emulsion are reviewed.Based on the process of hydroxylamine method and structure-activity relationship(SAR) of hydroxamic acid,some prospects of hydroxamic acid collectors synthesized by hydroxylamine method are pointed out.