Objective To find out the clinical significance of endovascular embolization in the treatment of cerebral arteriovenous malformation (AVM). Methods Clinically 37 patients were treated by endovascular embolization with NBCA and/or ONYX as embolic materials, followed by γ-knife therapy in 11 patients of them. Results After endovascular embolization, anatomical cure was achieved in 6 cases, more than 90% disappearance of the malformations in size in 11 cases, 70%~90% disappearance in 17 and less than 70% disappearance in 3. 2 cases of the group appeared periusion pressure-induced cerebral swelling, and other 2 cases suffered from hemorrhage after embolization. Conclusion Endovascular embolization is a safe and reliable method for treating AVM. In regard to some large AVMs or ones situated at important functional areas, endovascular embolization combined with surgery or γ- knife is an effective method for AVM with a high cure rate and a low morbiditv and mortalitv.