芹菜素
糖苷
立体化学
马洛特斯
化学
传统医学
细胞毒性T细胞
癌细胞系
类黄酮
癌细胞
生物
癌症
生物化学
医学
体外
抗氧化剂
古生物学
捕食
遗传学
作者
Nguyễn Hoàng Anh,Dương Thị Hải Yến,Nguyễn Thế Cuòng,Bùi Hữu Tài,Phạm Hải Yến,Phạm Thế Chính,Phạm Văn Cường,Nguyễn Hoài Nam,Phan Văn Kiệm,Su-Hyeon Cho,Seon Ju Park,Nguyễn Xuân Nhiệm
标识
DOI:10.1080/10286020.2022.2051494
摘要
Three new chromanes, malloapeltas J–L (1–3), and one new flavone C-glycoside, malloflavoside (4), together with four known compounds, apigenin 6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside (5), apigenin 6-C-β-D-glucopyranosyl-8-C-α-L-arabinopyranoside (6), apigenin 7-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside (7), and acantrifoside E (8) were isolated from the methanol extract of the leaves of Mallotus apelta. Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.
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