失语症
正电子发射断层摄影术
神经科学
神经影像学
心理学
认知
冲程(发动机)
语言功能
人脑
原发性进行性失语
神经可塑性
医学
病理
痴呆
计算机科学
物理
自然语言处理
疾病
失智症
热力学
作者
Daniela Perani,Stefano F. Cappa
出处
期刊:Handbook of Clinical Neurology
日期:2022-01-01
卷期号:: 151-165
标识
DOI:10.1016/b978-0-12-823384-9.00008-6
摘要
Positron emission tomography (PET) with perfusion and metabolism tracers, the first functional brain imaging method extensively applied to the study of the brain correlates of human cognitive function, has played a central role in the study of aphasia due to stroke. By showing the extent of intra-hemispheric and interhemispheric remote effects associated with focal damage and the reorganization of language networks during aphasia recovery, it has substantially contributed to the in vivo investigation of plasticity effects. Nowadays the main area of application of PET methods, including the new, powerful molecular imaging approaches using tracers binding to target biological receptors, is aphasia due to neurodegenerative disorders, and in particular the syndromes of primary progressive aphasia. In this extremely active research field, PET imaging is contributing to clinical diagnosis, correlation studies of specific aspects of linguistic impairment, and the in vivo exploration of the underlying pathologic processes.
科研通智能强力驱动
Strongly Powered by AbleSci AI