PI3K/AKT/mTOR通路
蛋白激酶B
癌症研究
生物
转录组
下调和上调
癌症
信号转导
基因
遗传学
基因表达
作者
Ying Jin,Yamei Chen,Huarong Tang,Xiao Hu,Shawna M. Hubert,Qian Li,Dan Su,Haimiao Xu,Yun Fan,Xinmin Yu,Qixun Chen,Jinshi Liu,Wei Hong,Yujin Xu,Huan Deng,Dapeng Zhu,Pansong Li,Yuhua Gong,Xuefeng Xia,Carl M. Gay
标识
DOI:10.1158/1078-0432.ccr-21-1943
摘要
PI3K/AKT pathway activation may be one potential mechanism underlying therapeutic resistance of SCLC. This finding warrants further investigation and provides a possible approach to reverse resistance to chemo/radiotherapy.
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