增强子
抄写(语言学)
RNA聚合酶Ⅱ
增强子rna
生物
基因
RNA聚合酶
核糖核酸
遗传学
DNA
计算生物学
细胞生物学
转录因子
基因表达
发起人
哲学
语言学
作者
Elizabeth M. Blackwood,James T. Kadonaga
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:1998-07-03
卷期号:281 (5373): 60-63
被引量:770
标识
DOI:10.1126/science.281.5373.60
摘要
In eukaryotes, transcription of genes by RNA polymerase II yields messenger RNA intermediates from which protein products are synthesized. Transcriptional enhancers are discrete DNA elements that contain specific sequence motifs with which DNA-binding proteins interact and transmit molecular signals to genes. Here, current models regarding the role of enhancers in the regulation of transcription by RNA polymerase II are presented.
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