生物
激酶
磷酸化
MAPK/ERK通路
蛋白激酶A
细胞生物学
MAPK级联
转录因子
丝裂原活化蛋白激酶
调节器
水杨酸
p38丝裂原活化蛋白激酶
丝裂原活化蛋白激酶激酶
信号转导
MAP激酶激酶激酶
生物化学
基因
作者
Yoshihisa Ueno,Riku Yoshida,Mitsuko Kishi-Kaboshi,Akane Matsushita,Chang‐Jie Jiang,Shingo Goto,Akira Takahashi,Hirohiko Hirochika,Hiroshi Takatsuji
出处
期刊:Plant Signaling & Behavior
[Informa]
日期:2013-06-01
卷期号:8 (6): e24510-e24510
被引量:33
摘要
WRKY45 transcription factor is a central regulator of disease resistance mediated by the salicylic acid (SA) signaling pathway in rice. SA-activated WRKY45 protein induces the accumulation of its own mRNA. However, the mechanism underlying this regulation is still unknown. Here, we report three lines of evidence showing that a mitogen-activated protein kinase (MAPK) cascade is involved in this regulation. An inhibitor of MAPK kinase (MAPKK) suppressed the increase in WRKY45 transcript level in response to SA. Two MAPKs, OsMPK4 and OsMPK6, phosphorylated WRKY45 protein in vitro. The activity of OsMPK6 was rapidly upregulated by SA treatment in rice cells. These results suggest that WRKY45 is regulated by MAPK-dependent phosphorylation in the SA pathway.
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